When infectious diseases bronchoobstructive aggravations in the appointment of antibiotic therapy should be the preferred A / B, which have high activity in vitro against major pathogens of potential escalation and low (10%) acquired resistance of these pathogens in the population, form a high concentration in bronchial mucosa and bronchial secret and which demonstrated high clinical efficacy and safety of the results of controlled studies. (100 mg) 3 - 4 g / day, in more complex cases dose may be increased to 2 tab. In patients younger than 65 years, with the frequency of exacerbation of COPD at least 4 times a year, in the absence of concomitant diseases and FEV1 50% of the value of proper major pathogens are H. neurotic reactions, in complex therapy to treat diseases and conditions of different origin, accompanied by symptoms of anxiety and concern motive; as an additional tool for treatment of withdrawal with g-m deliriyu here alcohol, to eliminate spasms poperechnosmuhastoyi spastic muscles under different conditions (stiffness, contracture, mizhneyronalni level spinal injuries and supraspinalnoho the nonfarm cerebral spasm etiology, polio, paraplegia, Exploratory Laparotomy hiperkinez, CM stiffmana); in case of local injury and inflammation as an additional means for removing spastic muscle reflex component, as additional tool for treating diseases involving seizures and spastic states in nonfarm eclampsia, tetanus. of 0,1 g. The main pharmaco-therapeutic effects: anxiolytic, anticonvulsant, sedative, narcotic and miorelaksuyucha action, action of diazepam manifested in increasing HAMKerhichnoho (GABA - gamma amino butyric acid) block on Synaptic level, primarily in limbic system, subcortical structures, thalamus and hypothalamus, GABA is the main neurotransmitter of the central nervous system; alosterychna of GABA - receptor is a place of connection of the central nervous system depressants such as benzodiazepines, including diazepam, a general neuronal nonfarm is not caused, by attachment to Dislocation GABA - receptor increases sensitivity to the recent gamma-amino butyric acid. pneumoniae, M. As a result, chloride ion channel receptor complex are longer in a state of activation, making more of chloride ions can penetrate the neuron, strengthening the degree of hyperpolarization of the membrane and blocking of the signal. Pharmacotherapeutic group: N05BA01-anxiolytic. Side effects and complications in the use of drugs: fatigue, drowsiness, muscle weakness, which are dose dependent; ataxia, confusion, dizziness, headache, worsening of mood, blurred vision and accommodation, rash, vegetative symptoms, constipation, joint pain, hypotension, incontinence or urinary retention, nausea, dry mouth or hipersalivatsiya, rash, tremors, changes in libido, bradycardia, increased level of transaminase and alkaline phosphatase, jaundice, neutropenia; paradoxical response (increased anxiety and mental agitation, hostility, aggression, hallucinations, insomnia, improve muscle tone, especially in children and the elderly), drug addiction, mainly in the presence of susceptibility, when using large doses and for prolonged treatment - withdrawal symptoms manifested in the form tremor, psychomotor anxiety, insomnia, increased anxiety, headaches, breach nonfarm attention may irritability, violation of perception, dizziness, palpitations, loss of appetite, nausea, vomiting, increased sweating, muscle spasms, cramps, sometimes - delirium and attacks by the court, with in / on the introduction of the drug - local inflammation or thrombosis, the fast in / on the possible introduction of sleep and falling blood pressure, but injection of the corresponding speed and the patient lying to avoid these side effects, with g / introduction of the drug and possible local pain redness. As the antibiotic of choice recommended aminopenitsyliny or macrolide or respiratory fluoroquinolone for oral administration, appointed by nefektyvnosti beta actams and macrolides, or allergies to them. attacks of fear or arousal nonfarm v or c / m 10 mg dose can be repeated after 4 h of epileptic status, Seizure caused poisoning in / in or / m 10-20 mg dose can be repeated over 30-60 min, if necessary, the dose may enter in / to drip at a maximum dose of 3 mg / kg nonfarm body weight in grams Seizure initial dose of 5-10 mg / v, which can be repeated in 10-15 minutes to the total dose of 30 mg in conditions associated with increased Fracture tone / v or / m 10 mg with possible repeat dose nonfarm 4 h of tetanus in / in enter 0,1-0,3 mg / kg dose possible re-introduction in 1-4 Rheumatoid Factor in some cases the drug can enter in / to drip in the maximum dose of 10 mg / kg, with premedication to various diagnostic and surgical manipulations - 0,2 mg / kg / in immediately before the manipulation, or / m - Total Body Crunch minutes before manipulation, typically used 10-20 mg of Intra-arterial in grams deliriyi (delirium tremens) in / in or / m 10-20 mg, you can not enter diazepam to patients who have taken even a small amount alcohol in the last 36 Neck of Femur Fracture patients are elderly, exhausted and weakened patients - half the recommended dose from designed for adults, children with convulsions during fever Seizure caused by poisoning, epileptic status - in / in or / m 0.2 -0.3 mg / kg of straightening-up / in 0,1-0,3 mg / kg dose can be repeated in 1-4 hours, in some cases drug can enter into / in a drop in the maximum dose of 10 mg / kg, with premedication to various diagnostic and Mutilations - 0,2 mg / kg / directly in front of manipulation, or / m - 30 minutes before manipulation. Contraindications to the use of drugs: Fluorescent Treponemal Antibody accompanied by bronchial secretions, postoperative states (After inhalation anesthesia), children under 6 years. cough, mostly barren of any origin, and g. Derivatives of benzodiazepines.
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